CAS No.: | 1094-61-7 |
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Formula: | C11h15n2o8p |
EINECS: | 214-136-5 |
Feature: | Stocked |
Usage: | Organic Chemical Material |
Status: | Solid State |
Customization: |
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Henan Sigma Aodeli New Material Technology Co., Ltd.
Sigma Aodeli Chemical Technology Co., LTD is an enterprise committed to the development, production, sales and transportation of chemical products. The company has a long-term cooperative relationship with Beijing Research Institute of Chemical Industry and its affiliated universities at home and abroad. It is a research and development enterprise of new chemical materials for the global chemical market demand. "Continuous innovation, quality assurance" is our purpose. It integrates the research and development, industrialization and marketization of innovative chemical new materials. The company has strong technical strength, advanced equipment, strict quality management system and quality after-sales service. Over the years, our products have been widely sold to many countries and regions, and we have established stable cooperative relations with traders and end users all over the world. Relying on a strong logistics system, we have established our own overseas warehouses in the United States, Mexico, Canada and the Netherlands. Hot local products can be shipped from overseas warehouses. Well received by local customers. It has become a powerful bridge between suppliers, traders and end users. We look forward to more cooperation with you.
Product Name | Nicotinamide Mononucleotide |
CAS | 1094-61-7 |
MF | C11H15N2O8P |
EINECS | 214-136-5 |
storage temp | -20°C |
Product specification | 1KG |
color | white |
delivery time | 7-10 safe delivery |
Description:Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.
β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.
Uses:β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments. NMN is a nucleotide derived from ribose and nicotinamide. Niacinamide (nicotinamide,) is a derivative of vitamin B3, also known as niacin.) As a biochemical precursor of NAD+, it may be useful in the prevention of pellagra.
β-Nicotinamide mononucleotide is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate β-NMN, which is subsequently converted to NAD+ by β-NMN adenyltransferase.At 50-100 μM, β-NMN has been used to enhance NAD biosynthesis and glucose-stimulated secretion in a Nampt+/- mouse model of metabolic disease, demonstrating a role for Nampt in β cell function.Furthermore, at 500 mg/kg/day, it has been shown to ameliorate glucose intolerance in high-fat diet-induced type 2 diabetes mice by restoring NAD+ levels.
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