| Kisspeptin 10 (human) Basic information |
| Product Name: |
Kisspeptin 10 (human) |
| Synonyms: |
MALIGNANT MELANOMA METASTASIS-SUPPRESSOR KISS-1 (112-121) (HUMAN);METASTIN (HUMAN, 45-54);METASTIN (45-54);METASTIN (45-54) AMIDE, HUMAN;METASTIN (45-54), HUMAN;KISSPEPTIN-13 (4-13) (HUMAN);KISS-1 GENE PRODUCT (HUMAN, 112-121 AMIDE);TYR-ASN-TRP-ASN-SER-PHE-GLY-LEU-ARG-PHE-NH2 |
| CAS: |
374675-21-5 |
| MF: |
C63H83N17O14 |
| MW: |
1302.44 |
| EINECS: |
|
| Product Categories: |
Peptide Receptors |
| Mol File: |
374675-21-5.mol |
| Kisspeptin 10 (human) Chemical Properties |
| density |
1.46±0.1 g/cm3(Predicted) |
| storage temp. |
-20°C |
| solubility |
DMF: 15 mg/ml; DMSO: 15 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.33 mg/ml |
| form |
A crystalline solid |
| pka |
9.96±0.15(Predicted) |
| Water Solubility |
Soluble in water at 1mg/ml |
| InChIKey |
RITKWYDZSSQNJI-INXYWQKQSA-N |
| Kisspeptin 10 (human) Usage And Synthesis |
| Description |
Kisspeptin-10, also called Metastin (45-54), is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product. It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)). Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM). It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling the potency of full length metastin. |
| Uses |
Kisspeptin 10 (human) is a powerful and specific activator for AXOR12 and hOT7T175 receptors. The Kisspeptin 10 (human) amide has been utilized in studies involving progesterone release from MA-10 cells and in experiments to induce gonadal differentiation in clownfish. |
| Shipping |
We guarantee 100% safe delivery from door to door, and in case of any accidents, we will resend the product free of charge until safe delivery. |
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