| Diclofenac sodium Basic information |
| description Uses Mechanisms of action Clinical Application |
| Product Name: |
Diclofenac sodium |
| Synonyms: |
N-(2,6-Dichlorophenyl)-o-amino sodium salt;sodium(o-((2,6-dichlorophenyl)amino)phenyl)acetate;sodium(o-(2,6-dichloroanilino)phenyl)acetate;sodiumdiclofenac;tsudohmin;AKOS B020028;2-(2,6-DICHLOROANILINO) SODIUM SALT;2-[(2,6-DICHLOROPHENYL)AMINO]-BENZENEACETIC ACID MONOSODIUM SALT |
| CAS: |
15307-79-6 |
| MF: |
C14H10Cl2NNaO2 |
| MW: |
318.13 |
| EINECS: |
239-346-4 |
| Product Categories: |
Other APIs;VOLATREN;Organics;Amines;Aromatics;Heterocycles;Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;API's;Lipid signaling;15307-79-6 |
| Mol File: |
15307-79-6.mol |
| Diclofenac sodium Chemical Properties |
| Melting point |
288-290°C |
| density |
0.781 g/cm3 |
| storage temp. |
room temp |
| solubility |
H2O: 50 mg/mL |
| pka |
4(at 25ºC) |
| form |
White solid |
| color |
White to Almost white |
| Water Solubility |
Soluble in water to 50mg/ml. |
| Merck |
14,3081 |
| BCS Class |
2 |
| Stability: |
Stable. |
| InChI |
InChI=1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1 |
| InChIKey |
KPHWPUGNDIVLNH-UHFFFAOYSA-M |
| SMILES |
C1(=CC=CC=C1CC([O-])=O)NC1=C(Cl)C=CC=C1Cl.[Na+] |
| CAS DataBase Reference |
15307-79-6(CAS DataBase Reference) |
| Diclofenac sodium Usage And Synthesis |
| description |
Diclofenac Sodium (Diclofenac sodium) is the sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. |
| Uses |
Diclofenac is a derivative belonging to the class of the non-selective non-steroidal anti-inflammatory drugs (NSAIDs). It exhibits analgesic, antipyretic and anti-inflammatory activity. Due to its poor solubility, the parenteral formulation of diclofenac sodium (Voltarol ampoules) currently available in Europe contains the solvents glycol and benzyl alcohol that allows intramuscular and intravenous administration. Diclofenac sodium has long been used to treat acute pain and inflammation, and is effective in various acute forms of pain. |
| Shipping |
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