| Amlodipine Besylate Basic information |
| Description Mechanism of action Clinical Use side effects Interaction with Combination Drugs References |
| Product Name: |
Amlodipine Besylate |
| Synonyms: |
Vazkor;3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona;3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate;AMlodipine bes;Amlodipine besilate (crystalline);2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate;raw material amlodipine besylate;Amlodipine Beaylate |
| CAS: |
111470-99-6 |
| MF: |
C26H31ClN2O8S |
| MW: |
567.05094 |
| EINECS: |
1312995-182-4 |
| Product Categories: |
BENICAR;AZD929;Aromatics;Dihydropyridine;Heterocycles;Fine Chemical;Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Amlodipine;111470-99-6;API |
| Mol File: |
111470-99-6.mol |
| Amlodipine Besylate Chemical Properties |
| Melting point |
199-201°C |
| storage temp. |
2-8°C |
| solubility |
DMSO: 20 mg/mL |
| form |
solid |
| pka |
8.6 |
| color |
white |
| Water Solubility |
Soluble in DMSO (20 mg/mL), water (10 mM), ethanol (14 mg/mL), and |
| Merck |
14,491 |
| BCS Class |
1 (CLogP) 3 (LogP) |
| InChIKey |
ZPBWCRDSRKPIDG-UHFFFAOYSA-N |
| CAS DataBase Reference |
111470-99-6(CAS DataBase Reference) |
| Uses |
A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive |
| Uses |
Angiotensin II inhibitor prodrug, antihypertensive |
| Uses |
Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats. |
| Shipping |
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