CAS No.: | 1341-23-7 |
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Formula: | C11h15n2o5+ |
EINECS: | 1308068-626-2 |
Feature: | Stocked |
Usage: | Organic Chemical Material |
Status: | Solid State |
Customization: |
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Henan Sigma Aodeli New Material Technology Co., Ltd.
Sigma Aodeli Chemical Technology Co., LTD is an enterprise committed to the development, production, sales and transportation of chemical products. The company has a long-term cooperative relationship with Beijing Research Institute of Chemical Industry and its affiliated universities at home and abroad. It is a research and development enterprise of new chemical materials for the global chemical market demand. "Continuous innovation, quality assurance" is our purpose. It integrates the research and development, industrialization and marketization of innovative chemical new materials. The company has strong technical strength, advanced equipment, strict quality management system and quality after-sales service. Over the years, our products have been widely sold to many countries and regions, and we have established stable cooperative relations with traders and end users all over the world. Relying on a strong logistics system, we have established our own overseas warehouses in the United States, Mexico, Canada and the Netherlands. Hot local products can be shipped from overseas warehouses. Well received by local customers. It has become a powerful bridge between suppliers, traders and end users. We look forward to more cooperation with you.
Product Name | Nicotinamide riboside |
CAS | CAS 1341-23-7 |
MF | C11H15N2O5+ |
EINECS | 1308068-626-2 |
storage temp | -20°C |
Product specification | 1KG |
color | white |
delivery time | 7-10 safe delivery |
Description:Nicotinamide Riboside (NR) is a next-generation vitamin B3 that has been found to be naturally-occurring in milk in trace amounts. The metabolism of NR is unique from that of other more commonly known forms of vitamin B3 , nicotinamide and nicotinic acid. Specifically, NR has been shown in a pre-clinical study to be the most effective form of vitamin B3 at increasing nicotinamide adenine dinucleotide (NAD+)2 .
Nicotinic acid (also known as niacin) and nicotinamide (also known as niacinamide) were discovered in the 1930's to be the factors that cured pellagra . Niacin is known to cause severe flushing . In 2004, nicotinamide riboside emerged as a newly discovered NAD+ precursor and does not bind to the receptor responsible for flushing.
NR has pre-clinically demonstrated that it is superior to both niacin and nicotinamide, both of which are standard forms of vitamin B3 commonly used in vitamin supplements and foods, at boosting NAD+2 . This is due to the fact that NR is not reliant upon a conversion step requiring the enzyme "NAMPT" , see Figure below. The activity level of NAMPT determines the amount of nicotinamide that is converted into NAD+ , which is why this particular step in the process is often referred to as the "rate limiting step". As normal aging occurs, the activity of NAMPT is thought to decrease. NR can be used by the cell to make NAD+ without this enzymatic step.
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