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| Acyclovir Basic information |
| Product Name: |
Acyclovir |
| Synonyms: |
1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-6h-purin-6-on;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-6h-purin-6-on;aciclovirum(latin);acielovir;cycloguanosine;Zoviax;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6h-purin-6-one;2-AMINO-9-(2-HYDROXY-ETHOXYMETHYL)-1,9-DIHYDRO-PURIN-6-ONE |
| CAS: |
59277-89-3 |
| MF: |
C8H11N5O3 |
| MW: |
225.2 |
| EINECS: |
261-685-1 |
| Product Categories: |
Valacyclovir Hydrochloride Monohydrate;Active Pharmaceutical Ingredients;PHARMACEUTICALS;Purine;Nucleotides and Nucleosides;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Amines;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;API's;Antiviral;Herpes Viruses;Anti-virals;THALOMID;inhibitor;59277-89-3 |
| Mol File: |
59277-89-3.mol |
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| Acyclovir Chemical Properties |
| Melting point |
256-257°C |
| Boiling point |
366.71°C (rough estimate) |
| density |
1.3654 (rough estimate) |
| refractive index |
1.8000 (estimate) |
| storage temp. |
2-8°C |
| solubility |
H2O: 0.7 mg/mL |
| form |
powder |
| pka |
pKa 2.27 (Uncertain);9.25 (Uncertain) |
| color |
white |
| Water Solubility |
Soluble in 1M HCl at 50mg/ml. Soluble in water at 0.7mg/ml. Also soluble in DMSO |
| Merck |
14,146 |
| BCS Class |
4,3 |
| Stability: |
Stable. Incompatible with strong oxidizing agents. |
| InChIKey |
MKUXAQIIEYXACX-UHFFFAOYSA-N |
| LogP |
-0.617 (est) |
| CAS DataBase Reference |
59277-89-3(CAS DataBase Reference) |
| IARC |
3 (Vol. 76) 2000 |
| Hazard Codes |
Xi,Xn |
| Risk Statements |
36/37/38-40-20/21/22 |
| Safety Statements |
22-24/25-36-26-23 |
| WGK Germany |
2 |
| RTECS |
UP0791400 |
| HazardClass |
IRRITANT |
| HS Code |
29335990 |
| Hazardous Substances Data |
59277-89-3(Hazardous Substances Data) |
| Toxicity |
LD50 in mice (mg/kg): >10,000 orally; 1000 i.p. (Schaeffer) |
| Description |
As it is evident from the chemical structure, acyclovir looks like a nucleoside analog of guanosine in side chain of which, instead of the traditional cyclic sugar residue a 2-hydroxyethoxymethyl acyclic side chain is present. Acyclovir possesses antiviral activity with respect to types 1 and 2 of herpes simplex, shingles virus, Epstein-Barr virus, and cytomegalovirus. |
| Chemical Properties |
white to light yellow crystal powder |
| Uses |
Acyclovir (Zovirax) is a synthetic purine analog derived from guanine. It exerts its effects on the herpes simplex virus (HSV) and varicella-zoster virus by interfering with DNA synthesis through phosphorylation by viral thymidine kinase and subsequent inhibition of viral DNA polymerase, thereby inhibiting viral replication. It is effective against HSV-1 and 2, varicella-zoster virus, Epstein-Barr virus, herpesvirus simiae, and cytomegalovirus. Acyclovir may be administered intravenously, orally, or topically. |
| Uses |
Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral; hypnotic. |
| Uses |
Inhibits cytomegalovirus replication; induces apoptosis |
| Shipping |
We guarantee 100% safe delivery from door to door, and in case of any accidents, we will resend the product free of charge until safe delivery. |
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
1.High quality with competitive price.
2. All purity>99%.
3. We are manufacturer and can provide high quality products with factory price.
4.Fast and safe delivery.
Q1: About the after-sale service of products
A: After purchasing the products from our factory, we have A professional technical team and after-sales team to serve you and solve all your problems in the future.
Q2: Can I get some samples?
A: Yes, we can provide samples, but the customer will pay the freight.
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Q4: How to confirm product quality before placing an order?
A: You can get free samples of some products. You just have to pay the shipping fee or arrange for the sample to be sent to us by express.
You can send us your product specifications and requirements and we will produce products according to your requirements.
Q5: What is your MOQ?
A: The minimum quantity we can order is 1kg.
But usually we can accept a smaller quantity, say 100g, at the cost of 100% sample charge.
Q6: Shipping Time?
A: We ship the parcel out in 1-2 days and offer tracking No.. Shipping time is different to different country. Please consult.
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